Paxil Helpful for Irritable Bowel Syndrome
Fri May 28, 2004 03:40 PM ET
NEW YORK (Reuters Health) - A popular antidepressant, Paxil, significantly improves the overall well-being of people with irritable bowel syndrome (IBS), researchers report.
Paxil is also known as Seroxat, and technically as paroxetine. In a statement, Dr. George Arnold of the University of Pittsburgh School of Medicine said that the findings highlight "the benefits of this drug as a potential new and improved treatment for IBS."
Arnold and colleagues report the results of their study of patients who had IBS, but were otherwise healthy, in the American Journal of Gastroenterology.
Initially, 98 patients were on a low or medium fiber diet for their condition and were switched to a high fiber diet for 7 weeks. In total, 25 patients reported a good response and stayed on this regimen.
The other 73 patients and another 12 who had already been on a high fiber diet were randomly assigned to take paroxetine or an inactive placebo daily while they continued with their high fiber diet.
At the end of 12 weeks, overall well-being increased in 63.3 percent of the paroxetine patients versus 26.3 percent of the placebo patients. The improvements were seen in non-depressed as well as depressed patients.
The paroxetine patients also reduced their avoidance of food, and their functioning at work was "marginally" better. However, there were no differences between groups in symptoms such as abdominal pain and bloating.
Given these findings, the researchers call for larger studies and evaluation of other similar antidepressants "to see whether they are as effective for the treatment of IBS as paroxetine appears to be."
SOURCE: American Journal of Gastroenterology, May 2004.
© Reuters 2004. All Rights Reserved.
Link Between Antidepressant Treatment and Increased Risk of Suicide
Link Between Antidepressant Treatment and Increased Risk of Suicide 30 May 2004 Source: Medical News Today Depression is a serious illness that increases the risk of suicide. This March, the FDA issued a Public Health Advisory in response to a...[Edit]
Posted in La Leva di Archimede (ENG) on May 31, 2004 11:28 AM
GlaxoSmithKline and antidepressant: Drug company experts advised staff to withhold data about SSRI use in children
Pharmaceutical Industry Drug company experts advised staff to withhold data about SSRI use in children Wayne Kondro Source: Canadian Medical Association Ottawa - An internal document advised staff at the international drug giant GlaxoSmithKline (GSK) to withhold clinical trial findings...[Edit]
Posted in La Leva di Archimede (ENG) on May 17, 2004 11:01 AM
Antidepressant, health risk and pharmaceutical fraud: How Could Drug Companies be so Evil?
How Could Drug Companies be so Evil? By Dr. Joseph Mercola According to the first comprehensive scientific review to include all available studies, including negative data that have long been withheld from public scrutiny by the pharmaceutical industry, four popular...[Edit]
Posted in La Leva di Archimede (ENG) on May 17, 2004 10:55 AM
Antidepressant (SSRI): Unpublished data reverses risk-benefit of drugs
Unpublished data reverses risk-benefit of drugs NewScientist.com news service 16:20 23 April 04 Unpublished studies on the effects of anti-depressant drugs on children suggest some are both ineffective and potentially harmful, according to a new review of research. The unpublished data contradict published...[Edit]
Posted in La Leva di Archimede (ENG) on April 26, 2004 09:36 AM
Antidepressant-Suicide Link to Be Probed
Antidepressant-Suicide Link to Be Probed Fri Apr 16,11:00 AM ET By LAURAN NEERGAARD, AP Medical Writer Source: Yahoo News WASHINGTON - A House committee says it will investigate whether the Food and Drug Administration (news - web sites) fully disclosed...[Edit]
Posted in La Leva di Archimede (ENG) on April 20, 2004 09:49 AM
The FDA defends itself: Expert Kept From Speaking at Antidepressant Hearing
News on the suicidal effects of antidepressants denied by FDA's associate director of medical policy, Dr. Robert Temple. It was "inappropriate to present as an F.D.A. conclusion an analysis of data that were not ripe", he said. Fired the doctor...[Edit]
Posted in La Leva di Archimede (ENG) on April 16, 2004 03:01 PM
Study Advises Against Drugs for Children in Depression
Study Advises Against Drugs for Children in DepressionBy GARDINER HARRISPublished: April 9, 2004Original Source: New York TimesPediatricians and family physicians should not prescribe antidepressants for depressed children and adolescents because the drugs barely work and their side effects are often...[Edit]
Posted in La Leva di Archimede (ENG) on April 9, 2004 02:07 PM
FDA finally concedes antidepressant suicide risk after 13-year fight for warning
FDA finally concedes antidepressant suicide risk after 13-year fight for warningSource: eMediaWire“We are pleased the FDA is finally requiring the manufacturers of these drugs to include warnings about the suicide risk, however, it should not have taken over a...[Edit]
Posted in La Leva di Archimede (ENG) on March 25, 2004 12:14 PM
Antidepressants May Cause Depression and Suicidality
Antidepressants May Cause Depression and SuicidalityYael WaknineMarch 22, 2004 — The U.S. Food and Drug Administration (FDA) has asked manufacturers of the several antidepressant drugs to include in their labeling a warning statement that recommends close observation of adult and...[Edit]
Posted in La Leva di Archimede (ENG) on March 23, 2004 11:56 AM
FDA urges caution on Prozac
Doctors are told to watch anti-depressant patients for suicidal thoughts; Stronger warning labels advised The Food and Drug Administration told doctors yesterday to carefully monitor patients on 10 popular anti-depressants for suicidal thoughts and asked manufacturers to add the warning...[Edit]
Posted in La Leva di Archimede (ENG) on March 23, 2004 10:23 AM
Prozac: Bitter Pill for David Healy: Academia Under Pharma Influence
Bitter Pill for David Healy: academia under pharma influenceSource: Alliance for Human Research Protection May 21, 2002 One wonders how many embarrassing causes celebres are needed before academic institutions take back control of the university from the corrosive influence of...[Edit]
Posted in La Leva di Archimede (ENG) on March 15, 2004 04:58 PM
Prozac: The Eli Lilly Suicides
THE LILLY SUICIDESA peculiar and toubling caseby Richard DeGrandpreTHE WITNESSIn the final days of the 20th century, a North Wales psychiatrist named David Healy conducted a curious study, and with more than a curious result. Twenty volunteers with no history...[Edit]
Posted in La Leva di Archimede (ENG) on March 15, 2004 04:31 PM
The Myth Of Psychiatry And Pharmaceutical Drugs
Disorders made to order: pharmaceutical companies have come up with a new strategy to market their drugs: First go out and find a new mental illness, then push the pills to cure it. Mother Jones, July-August, 2002, by Brendan I....[Edit]
Posted in La Leva di Archimede (ENG) on March 3, 2004 04:38 PM
Pharma makers withhold suicide data in drug studies
According to an article in the Washington Post, the makers of popular antidepressants such as Paxil, Zoloft and Effexor have refused to disclose the details of most clinical trials involving depressed children, denying doctors and parents crucial evidence as they...[Edit]
Posted in La Leva di Archimede (ENG) on February 18, 2004 12:21 PM